Age-Related Vision Loss Helped
with Vitamin Bs and Folic Acid

Again - the Bs have it! An Interesting Correlation between Age-Related Macular Degeneration (AMD) and Homocysteines

We have covered the topic previously how Vitamin Bs and Folic Acid help to reduce levels of homocysteines in the blood and its correlation to heart disease, migraines and stress. Now it appears that it also plays a role in Age-Related Macular Degeneration (AMD). Vision loss in older Americans is prevalent, with AMD being one of the leading causes of vision loss. This has been difficult to treat with the only known prevention being to stop smoking.

The latest research studies have found that there is a connection between AMD and the amounts of homocysteine in the blood. Research according to the February 23rd issue of Archives of Internal Medicine has shown that having high levels of homocysteine can be destructive to the linings of blood vessels, and that treatment with vitamin B6, vitamin B12 and folic acid appears to lessen the amount of homocysteine levels and may help to turn around this blood vessel dysfunction.

A randomized, double-blind clinical trial involving 5,442 women age 40 and older who already had heart disease or at least three risk factors was performed by William G. Christen, Sc.D., of Brigham and Women's Hospital and Harvard Medical School, Boston, and his colleagues . Of these, 5,205 did not have AMD at the beginning of the study. In April 1998, these women were randomly assigned to take a placebo or a combination of folic acid, pyridoxine hydrochloride (vitamin B6) and cyanocobalamin (vitamin B12). The study was conducted with participants being tracked all the way through July 2005 and also were followed for the development of AMD through November 2005.1,2

Over an average of 7.3 years of treatment and follow-up, 137 new cases of AMD were documented, including 70 cases that were visually significant (resulting in a visual acuity of 20/30 or worse). Of these, 55 AMD cases, 26 visually significant, occurred in the 2,607 women in the active treatment group, whereas 82 of the 2,598 women in the placebo group developed AMD, 44 cases of which were visually significant. Women taking the supplements had a 34 percent lower risk of any AMD and a 41 percent lower risk of visually significant AMD. "The beneficial effect of treatment began to emerge at approximately two years of follow-up and persisted throughout the trial," the authors write. 1,2

"The trial findings reported herein are the strongest evidence to date in support of a possible beneficial effect of folic acid and B vitamin supplements in AMD prevention," the authors write. Since they apply to the early stages of disease development, they seem to represent the first identified way—other than not smoking—to reduce the risk of AMD in individuals at an average risk. "From a public health perspective, this is particularly important because persons with early AMD are at increased risk of developing advanced AMD, the leading cause of severe, irreversible vision loss in older Americans."1,2

What does this mean for you? If you have noticed a gradual deterioration of your eyesight, it may behoove you to take a another look at your diet and determining with the advice of your doctor as to whether taking a high quality b vitamin and folate supplementation such as B-Active.*


1.     William G. Christen; Robert J. Glynn; Emily Y. Chew; Christine M. Albert; JoAnn E. Manson. Folic Acid, Pyridoxine, and Cyanocobalamin Combination Treatment and Age-Related Macular Degeneration in Women: The Women's Antioxidant and Folic Acid Cardiovascular Study. Archives of Internal Medicine, 2009; 169 (4): 335 DOI: 10.1001/archinternmed.2008.574

2.      JAMA and Archives Journals (2009, February 23). Vitamin B And Folic Acid May Reduce Risk Of Age-related Vision Loss. ScienceDaily. Retrieved February 28, 2009, from /releases/2009/02/090223221336.htm  

*While Active 8 Products does not claim to diagnose or treat any disease and you should consult with your doctor if unsure as to whether you should take B-Active; these research studies indicate that it is possible that if you suffer from migraines that you could experience the same benefits of vitamin b and folate supplementation. B-Active is time-released for maximum benefits and composed of B6, B12 and Folic Acid. It is 100% guaranteed &  fully refundable if you are not satisfied for any reason.

Additional Resource Links You Might Like in Regards to Folic Acid:

Did you know that you get more value for your money with B-Active? It's true! Over-the-counter B vitamins are eliminated from your body once it determines what you need at the time you ingest it. But not B-Active, it's time-released so that it stays in your system all day!  Our very own B-Active contains not only vitamin B6, but B12 and folic acid as well.

B-Active is time-released for maximum benefit!
Get more for your money with B-Active!

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