Omega-3s and Your Heart Health

Omega-3s May Make Survival Rates Better for Chronic Heart Failure Patients

News as released from VRP :
Scientists have determined that adding omega-3 fatty acids to a daily supplementation routine may help better the survival rates of heart failure patients and help less admissions to hospital emergency rooms, especially those with chronic heart failure.

Previous research has indicated that omega-3 fatty acids from deep sea fish oils can perform a crucial role in heart and circulatory health. However, there have evidently not been any large-scale trials that looked at how effective omega-3 fatty acids could be in helping to prevent heart failure. As a result, scientists decided to conduct a study as to whether omega-3 fatty acids could help improve mortality rates in a sizeable number of patients with symptomatic heart failure caused for any reason.

In the randomized, double-blind, placebo-controlled research study, scientists gave 3,494 patients, with chronic heart failure of  the New York Heart Association class II–IV, 1 gram of omega-3 fatty acids on a daily basis. The second group contained 3,481 people that received only a placebo. All patients were followed up for a medium of approximately 3.9 years.

During the trial, 955 (27 percent) of the patients died from any cause in the omega-3 group and 1,014 (29 percent) in the placebo group. In the omega-3 group, 1,981 (57 percent) patients died or were admitted to a hospital for cardiovascular reasons compared to 2,053 (59 percent) in the placebo group. In heart failure patients assigned to receive omega-3s, this amounted to a 9 percent relative reduction in mortality rates, and an 8 percent relative reduction in hospital admissions for cardiovascular reasons compared to subjects taking the placebo.1,2

The researchers concluded, “A simple and safe treatment with n-3 PUFA [omega-3 fatty acids] can provide a small beneficial advantage in terms of mortality and admission to a hospital for cardiovascular reasons in patients with heart failure.”1, 2


1. Authors listed as GISSI-HF investigators. Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial. The Lancet. Published online ahead of print. August 31, 2008.


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